Jouault T, Fradin C, Trinel PA, Poulain D (2000): Candida albicans-derived beta-1,2-linked mannooligosaccharides induce desensitization of macrophages
Infect. Immun. 68 (2): 965-968.

Candida albicans beta-1,2-oligomannosides stimulate macrophage tumor necrosis factor alpha (TNF-alpha) but not NO release. This stimulation desensitized macrophages by altering beta-1,2-oligomannoside-dependent TNF-alpha production and lipopolysaccharide-dependent TNF-alpha and NO secretion. Desensitization was not related to tyrosine phosphorylation signal transduction but was transferred by culture supernatants in which arachidonic acid derivatives were evidenced.